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Testosterone Therapy Health Risk Eclipses Benefits

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Testosterone Therapy: Health Risks Eclipse Benefits

With mounting evidence suggesting serious health risks connected to testosterone therapy, doctors healthcare professionals have become cautious in suggesting Low T supplements to patients. Testosterone therapy use has almost quintupled in the last 11 years with over 5.5 million prescriptions and $2 billion in supplement sales. However, there is an increased risk of health disorders from the therapy. Recent studies have indicated that the use of Low T supplements without clinical diagnosis of testosterone deficiency may result in heart attack, stroke, or cardiovascular adverse events leading to death.

Post-marketing reports suggest higher prostate-specific antigens, a leading cause of prostate cancer, among testosterone therapy patients. Abnormal increase in blood counts, clots, metabolic disorders, and a variety other health problems may cause Low T users to suffer more than they gain.

According to Mayo Clinic experts, testosterone also leads to male breast abnormalities, dermatological disorders, and sleep apnea, which may worsen quality of life.

Testosterone Therapy Side Effects

  • Wrongful Death: Low T supplements result in the onset and aggravation of existing heart disorders, which may cause testosterone death.
  • Cardiovascular Disorders:  Testosterone therapy may cause 30 percent greater risk of cardiovascular problems. Heart attack and stroke are most reported disorders connected to the treatment.
  • Blood Clots: Low T supplements have been linked to the heightened risk of clotting within arteries. It leads to thrombotic events that prevent blood circulation to heart, brain, and lungs.
  • Metabolic and Sleep Disorders: Reversing age-specific testosterone formation results in metabolic syndrome, sleep apnea, rise in cholesterol level, and diabetes, impacting the life quality of users.
  • Prostate Cancer: Researchers have discovered an increase in prostate-specific antigens caused by Low T supplements. It may result in prostate cancer.
  • Endocrine Disparity
  • Worsening kidney and liver problems

FDA on Testosterone Therapy

Testosterone supplements are recommended for medical conditions, such as hypogonadism. The manufacturer claims that these help prevent natural decline in the hormone level caused by age-related factors. The federal regulator also advises for adequate clinical testing prior to using Low T supplements to boost testosterone production. A boxed warning mandated by the FDA for AndroGel and Testim, two Low T supplements commonly used by people to stay young and improve health, cautions users against secondary exposure that may cause children and women to have fast and unusual psychological and sexual behavioral changes.

Testosterone Therapy Lawsuits

The recent researches highlighting heart disorders and death due to Low T supplements have resulted in a number of testosterone therapy lawsuits. A recent Wall Street Journal report, claiming an abrupt end of a testosterone trial by the National Institutes of Health in 2009 because of high rate of cardiovascular problems in patients, have added further support to the allegations by litigants.

Anyone who has suffered from injuries following the use of Low T supplements can file a testosterone therapy lawsuit seeking product liability against the medication manufacturer.  Contact an experienced drug injury attorney to evaluate your claim.

If you or a loved one have experienced a testosterone replacement therapy injury after undergoing low testosterone therapy, please contact our team of lawyers today for a free case evaluation at:

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    CBS Reports Testosterone Therapy Can Cause Heart Attack, Stroke and Death

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    httpv://www.youtube.com/watch?v=kogkW1lil5s

    Dr. Jon Lapook of CBS News reviewed the recent JAMA article showing a 29% increased risk for men over 60 undergoing testosterone replacement therapy and suffering from a blood clot, stroke or other similar attack.  The video likewise contains the comments of Dr. Steve Missen of the Cleveland Clinic and Dr. Elizabeth Kavalere, a urologist.

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      What Were the Results of the JAMA Study on Testosterone Replacement Therapy?

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      What Were the Results of the JAMA Study on Testosterone Replacement Therapy?

      The JAMA study looked at two groups of veterans with medical problems in the VA Health System, including (1) those who were taking testosterone therapy to treat low testosterone and (2) those who were not. The group of veterans taking testosterone therapy were generally healthier than the veterans who were not taking testosterone therapy. The study found that in a three year period the men on testosterone therapy suffered 29% more heart attacks, strokes and deaths than the men who were not on testosterone therapy. The study’s authors ruled out other diseases as a cause of this association.

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        Are Patients Being Injured With Testosterone Therapy While Companies Make Millions in Profits?

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        You may be visiting this website because you or a loved one has experienced a testosterone replacement injury including a testosterone stroke, a testosterone heart attack or a testosterone blood clot. If so, please keep reading.

        In the opinion of some, large businesses have turned testosterone-boosting drugs into a $2 billion marke. In a new study in the Journal of the American Medical Association there are concerns over Low T therapy: it may cause cardiovascular events such as heart attacks, blood clots, strokes and pulmonary embolism.   These would result in a low testosterone injury.

        Over the past couple of years, therapies such as Eli Lilly’s Axiron; AbbVie’s AndroGel; and Auxilium and GlaxoSmithKline’s Testim have taken off like a rocket as companies rolled out new products and amped up their advertising. IMS Health says sales of testosterone drugs grew by 90% over 5 years, reaching $1.9 billion in 2011. By 2017, the entire testosterone market is expected to hit $5 billion.

        Researchers analyzed the medical records of 8,709 male veterans with low testosterone who had a coronary angiogram. Of that group, 1,223 men began testosterone therapy after their procedure. The rate of death, heart attack or stroke hit 25.7% in that group, compared with 19.9% in the men who didn’t use testosterone drugs

        After controlling for various factors, the researchers calculated a 29% increase in risk for the men who used testosterone. And as Forbes points out, the change in risk was the same in men who had coronary artery disease as in men who didn’t–and the testosterone group had a lower risk profile to begin with.   The research isn’t conclusive; as an observational study, it’s more of a flag for future study than a clear warning. A JAMA editorial points out that the analysis includes little information about whether the drugs were prescribed according to label guidelines. But the editorial also advises caution. The number of prescriptions is growing quickly, and drugmakers continue to aggressively advertise the treatments.   As the editorial points out, some men are using testosterone for lifestyle reasons, rather than to replace actual, clinical deficits in their hormone levels–for antiaging and “physical enhancement,” for instance, JAMA notes. Does any increase in risk apply to these younger, perhaps healthier, men?

        Here’s where pharma advertising comes in. Earlier this year, Consumer Reports urged men to be wary about starting hormone therapy, saying most men really don’t need the drugs. The magazine cited drugmakers’ big-time spending on marketing the products, with promotional expenses up to $100 million in 2012 from $14 million in 2011.   For 2013, that figure may grow substantially. For the first half of this year alone, AbbVie spent more than $45 million promoting Androgel, which is now its second-best-selling drug. Still, AbbVie, Lilly and other drugmakers say they only market their testosterone products for men whose hormone levels are clinically low.   For now, the data on testosterone use is far from comprehensive. A National Institutes of Health study is set to wrap up next year. In the meantime, the JAMA researchers say their study at least offers some perspective. “Prior to this study, we didn’t know much about the cardiovascular risk,” said lead author Michael Ho, a cardiologist with the Veterans Affairs Eastern Colorado Health Care System.

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          Dr. Larry Mulkerin Outlines Why The Low T Treatment Plan Was Made Up To Make Money

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          Testosterone Therapy Injury Lawyer Asks if Low T Treatment Plan Was “Made Up”

          Dr. Larry Mulkerin is a retired clinical professor and oncologist who lives in Walla Walla. He is a former U.S. Army Green Berets medical officer with experience in the Middle East, and he also is the author of “The Ayatollah’s Suitcase,” a novel available at amazon.com and other online book retailers. Dr. Mulkerin explains in his article that “The pharmaceutical industry wants men to think their sex lives, muscle mass and energy levels are in trouble because of — oh my goodness — low testosterone.”

          He gives six examples on why this is only a fiction:

          1. AbbVie, the manufacturer of AndroGel spent $80 million of the $3.47 billion the industry spent in 2012, according to The New York Times in an Oct. 15, 2013, article. Direct-to-consumer advertising is a strong driver of medical costs and it often promotes ineffective or dangerous products. It’s hard to convince patients that they were suckers of a sales pitch.
          2. The cost of one bottle, about one month’s supply, is quoted at more than $400.
          3. The risks from treatments are uncertain, but the list extends from prostate cancer to shortened life expectancy. Other concerns have included liver damage, overproduction of red cells, prostate enlargement, sleep apnea and worsening heart failure. A study of 8,709 men was published Nov. 6, 2013 in the Journal of the American Medical Association. The men in that study all had risks for vascular disease and testosterone levels below 300 nanograms per milliliter. The study was stopped because the testosterone-treated group had more heart attacks and strokes, and they also had a higher death rate — 27.7 percent compared to 19.9 percent in the untreated group.
          4. Doctors use average testosterone levels in young men as the standard for determining what is normal and what is not. It’s not reliable. Individuals vary and the response to treatment is different depending on what you measure: muscle mass, strength, sexual function and so on.
          5. There’s a lot we don’t understand about possible benefits and risks. The chemistry is complicated. For example, 80 percent of the female hormones in men arise from a chemical reaction with testosterone. More testosterone means more female hormones.
          6. I suspect the most important thing we have to learn is that the basic concept was a mistake, one we’ve made before. We haven’t seemed to benefit from history. What warnings did we have?

          Dr. Mulkerin goes on in his study to examine what may be causing other problems with Low T and hormone/growth therapy, which costs thousands of dollars and may have limited benefits.

          Testosterone medications, like AndroGel, Androderm, Axiron, Depotestosterone, Fortesta, and Testim, could increase the percentage of red blood cells in your blood. The increase in red blood cells can cause strokes, blood clots, and possibly death.

          If you or a loved one have experienced a testosterone replacement therapy injury after being diagnosed with Low T, please contact our team of lawyers today for a free case evaluation at:

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            Center for Comprehensive Cardiovascular Care at Saint Louis University Hospital Warns of Risks Associated with Testosterone Replacement Therapy

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            Risks Associated with Testosterone Therapy Injury

            Male hormone therapy can put men at risk, says a new study by the JAMA.  Dr. Richard Lee, the co-director of the Center for Comprehensive Cardiovascular Care at Saint Louis University Hospital is “concerned” about the “not so simple” problem about increased risk of cardiovascular events.

            The study with JAMA shows a 29% increased risk of cardiovascular related events, such as heart attack, stroke, blood clot, or pulmonary embolism.  Dr. Lee recommends all patients immediately consult with their doctors about a treatment plan in light of these risks.

            Testosterone medications, like AndroGel, Androderm, Axiron, Depotestosterone, Fortesta, and Testim, could increase the percentage of red blood cells in your blood. The increase in red blood cells can cause strokes, blood clots, and possibly death.

            If you or a loved one have experienced a testosterone replacement therapy injury after being diagnosed with Low T, please contact our team of lawyers today for a free case evaluation at:

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              Dr. Michael Ho Discusses JAMA Article on Heightened Risks Associated with Low Testosterone Therapy

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              There Are Heightened Risks with Testosterone Therapy, Including Heart Attack, Strokes and Blood Clots

              Dr. Michael Ho, an Associate Professor of Medicine at the VA Eastern Colorado Health Care System in Denver, Colorado, explains and discusses the JAMA Article entitled Association of Testosterone Therapy With Mortality, Myocardial Infarction and Stroke in Men with Low T-levels” as published on November 6, 2013.

              This study looked at men undergoing cardiac angiography in the VA health system, who also had low T levels.  The study shows a relationship with an increased risk of health problems associated with Low T levels and were on testosterone therapy.   There was no difference as to whether the therapy was via patches or shots. 82% of the men undergoing Low T therapy filled more than 1 prescription, signifying long term use of the therapy.

              This was a retrospective study only, per Dr. Ho, but it “raises a question about the safety of testosterone therapy” to Dr. Ho.  He believes a study should be undertaken as to the risks vs. benefits of testosterone therapy.

              Testosterone medications, like AndroGel, Androderm, Axiron, Depotestosterone, Fortesta, and Testim, could increase the percentage of red blood cells in your blood. The increase in red blood cells can cause strokes, blood clots, and possibly death.

              If you or a loved one have experienced a testosterone replacement therapy injury after being diagnosed with Low T, please contact our team of lawyers today for a free case evaluation at:

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                Testosterone Therapy: The Risks Outshine the Benefits

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                Testosterone Therapy Lawsuit: Side Effects Outshine Benefits

                A 40-year-old man from Jackson took testosterone therapy for a year after he saw several “low-T ads” promoting hormone medications. He felt the need to have testosterone injections to overcome age-related androgenic hormone deficiency. To his dismay, he experienced severe heart pain and respiratory distress three months after discontinuing the testosterone supplements. A detailed diagnosis revealed that he had a blockage obstructing blood flow to his lungs.  Testosterone supplements caused him to develop blood clots in his leg. The clot travelled to his lungs prior to being developed into a blockage that prevented blood supply from the heart to lungs and caused him to suffer a stroke.

                The past decade has witnessed a noticeable increase in the use of testosterone therapy by the middle-aged and older men. More than 5.5 million prescriptions resulted in the selling of testosterone supplements worth $2 billion in 2012, a marked rise from around $300 million a decade ago. However, medical researches as well as post-marketing surveys have highlighted a significant rise in testosterone therapy side effects. Heart attacks, blood clots, metabolic disorders, the risk of cancer, and strokes have led to the filing of a number of testosterone therapy lawsuits across the United States.

                Testosterone Therapy Side Effects

                • Testosterone death
                • Heart attack
                • Metabolic disorder
                • Other cardiovascular problems, including blockages, stroke
                • Development of blood clots and risk of pulmonary embolism
                • Diabetes and high cholesterol
                • Increase in kidney and liver ailments
                • Enhanced risk of prostate cancer

                FDA Warning on Testosterone Supplements

                In 2000, the FDA issued a public advisory against the use of testosterone therapy for “age-associated” reduction in the sex hormone. The Endocrine Society’s Clinical Practice Guidelines also recommends the use of testosterone therapy only after certified through clinical diagnosis and consistent symptoms of low testosterone.

                However, there has been widespread off-label use and prescription of testosterone supplements, and it has almost gone up four times in the last 10 years. Consequently, there has been a spurt in testosterone therapy side effect instances.

                In 2009, the FDA ordered for black box warnings on two most prescribed testosterone-enhancing gels, AndroGel and Testim. According to the label changes added, these two supplements pose health risks to women and children when they come into contact. Women may develop male sexual characteristics, hair in the chest, and enlarged genitals. Abnormal genital intensification, violent and increased sexual behavior, and rapid increase in pubic hair growth are a few side effects that children suffer from when exposed to testosterone medications.

                Testosterone Therapy Research Studies

                • According to Mayo Clinic, regular treatment with testosterone therapy may result in sleep apnea, dermatological side effects, growth of male breasts, and prostate tumor.
                • A November 2013 report published JAMA medical journal claims that testosterone therapy causes 29 percent higher risk of cardiovascular side effects. Based on the study of the medical records of 1,223 men treated with testosterone supplements, it found that at least 15 percent of them had serious heart disorders, resulting in 67 deaths, 23 heart attacks, and 33 strokes. The study blamed large-scale use of testosterone medications by men without being sure of their needs.
                • Chicago Tribune Business reported in September 2013 that a meta-analysis of 27 independent research studies had cited a two-fold increased risk of heart problems and stroke in men using testosterone therapy.

                Testosterone Therapy Lawsuit

                Off-label promotion and prescription of testosterone supplements has caused a number of deaths and serious cardiovascular disorders. Despite research studies and FDA warning, manufacturers have been steadfast in their promotional campaigns resulting in consumers using the medications as a safe and secure way to increase their sex hormones. However, after the recent disclosures by the American Medical Association and media reports indicating deaths, heart disorders, lung problems, and strokes caused by these supplements, a number of people have come forward to file testosterone therapy lawsuits seeking product liability.

                Testosterone medications, like AndroGel, Androderm, Axiron, Depotestosterone, Fortesta, and Testim, could increase the percentage of red blood cells in your blood. The increase in red blood cells can cause strokes, blood clots, and possibly death.

                If you or a loved one have experienced a testosterone replacement therapy injury after being diagnosed with Low T, please contact our team of lawyers today for a free case evaluation at:

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                  Testosterone Therapy May Lead to Fatal Cardiovascular Risks, Claims Research Study

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                  Testosterone Therapy Leads to Fatal Cardiovascular Risks, Claims Research Study

                  In November 2013, the Journal of the American Medical Association reported findings that linked testosterone therapy side effects to death and serious heart problems. Researchers from Denver-based VA Eastern Colorado Health Care discovered hundreds of instances where men had suffered from death, stroke, and heart attacks following administration of testosterone therapy.  The study analyzed details of 1,223 men treated with the hormone enhancement medications and reported that 33 suffered from stroke, 23 were hospitalized, and 67 died within 18 months of having testosterone therapy.

                  Researchers claimed that there was at least 29 percent increase in the risk of cardiovascular problems in men treated with testosterone therapy. Supported by a team of experts from the University of Texas, they studied the medical history of 9,000 male veterans who underwent angiography between 2005 and 2011 because of blockage in coronary artery. It was found that those used testosterone supplements had 30 percent higher rate of cardiovascular adverse events resulting in death, stroke, or heart attack. The study held aggressive promotion and off-label prescription of testosterone supplements responsible for increase in the risk of side effects.

                  According to a 2013 Wall Street Journal report, a high risk of heart problems linked to testosterone therapy side effects forced researchers sponsored by the National Institutes of Health to call off a hormone treatment trial for older men in 2009.

                  Testosterone Therapy Health Risks

                  Testosterone hormone plays a key role in helping sexual drive, concentration, muscle strength, sperm creation, energy level, and bone health in men. However, the hormone production decreases in men after they complete 30 years. Many also suffer because of hypogonadism or reduced functioning of sex glands, which results in diminished testosterone production. To overcome such conditions, men resort to administration of testosterone supplements in the form of injection, patch, and gel. AndroGel, Testim, Fortesta, Depo-Testosterone, Bio-T-Gel, Axiron, Cypionate, Delatestryl, Androderm, Striant, Androgel, and Testopel are among the most used testosterone therapy medications.

                  Major health risks linked to testosterone therapy include

                  • Death
                  • Aggravation of preexisting heart, kidney, or liver disorders
                  • Cardiovascular disorders leading to heart attack and stroke
                  • Blood clots in the leg causing the potential risk of artery blockages
                  • Metabolic disorders resulting in diabetes and high cholesterol
                  • Risk of prostate cancer
                  • Endocrine imbalance

                  Mayo Clinic warns of the risk of sleep apnea, development of enlarged male breasts, prostate tumor, and skin problems among testosterone therapy side effects.

                  FDA Warning on Testosterone Therapy

                  The FDA has added black box warnings on AndroGel and Testim, two most used testosterone therapy gels, for raising the risk of secondary exposure. Issued in 2009, the warning cautioned about the potential risk of increased violent behavior, abnormal genital growth, premature sexual behavior, and accelerated bone growth in children and women when exposed to these testosterone medications used by men at home.

                  Earlier in 2000, the FDA cautioned against universal use of AndroGel, suggesting that the medication is only for men with hypogonadism and not for “age-associated” reduction in the testosterone level. However, there is widespread off-label promotion of these testosterone drugs notwithstanding the FDA advisory. AndroGel maker AbbVie is facing a whistleblower lawsuit for pressing for off-label promotion and use of its “low-T” products.

                  Testosterone medications, like AndroGel, Androderm, Axiron, Depotestosterone, Fortesta, and Testim, could increase the percentage of red blood cells in your blood. The increase in red blood cells can cause strokes, blood clots, and possibly death.

                  If you or a loved one have experienced a testosterone replacement therapy injury after being diagnosed with Low T, please contact our team of lawyers today for a free case evaluation at:

                  CALL: 1-800-632-1404

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                    Study Finds Testosterone Therapy Causes Strokes and Heart Attacks

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                    Testosterone Therapy and Cardiac Risk from Israel Barken on Vimeo.

                    Testosterone Lawyer Reports on Study: Testosterone Therapy May Cause Heart Attacks

                    Dr. Israel Barken, the medical director of the Prostate Cancer Research and Educational Foundation, discusses potential harms of undergoing testosterone replacement therapy. He discusses the recent study that reflected an increased risk of cardiovascular events among men.  The study at issue took place between 2005 and 2011 in the Veteran Affairs (VA) system.  The conclusion was that “among a cohort of men in the VA health system who underwent coronary angiography and had a low serum testosterone level, the use of testosterone therapy was associated with an increased risk of adverse outcomes.  These findings may inform the discussion about the potential risks of testosterone therapy.”

                    Testosterone medications, like AndroGel, Androderm, Axiron, Depotestosterone, Fortesta, and Testim, could increase the percentage of red blood cells in your blood. The increase in red blood cells can cause strokes, blood clots, and possibly death.

                    If you or a loved one have experienced a testosterone replacement therapy injury after being diagnosed with Low T, please contact our team of lawyers today for a free case evaluation at:

                    CALL: 1-800-632-1404

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